| Index | Ligand Name | Structure | PDB code | Compound Potency nM |
| 1 | via | Crystal structure of Human Phosphodiesterase 5 complexed with Sildenafil(Viagra) | 1udt | 0.5 |
| 2 | vdn | Crystal structure of Human Phosphodiesterase 5 complexed with Vardenafil(Levitra) | 1uho | 0.6 |
| 3 | cia | Crystal structure of Human Phosphodiesterase 5 complexed with tadalafil(Cialis) | 1udu | 0.9 |
| 4 | ni0 | Crystal structure of PDE5A in complex with its inhibitor | 4g2w | 1.6 |
| 5 | via | Crystal structure of PDE5 in complex with sildenafil | 2h42 | 2.4 |
| 6 | 5bo | Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors | 3sie | 13.3 |
| 7 | 24e | Crystal structure of PDE5 in complex with inhibitor 5R | 4md6 | 17 |
| 8 | 5ba | Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors | 4i9z | 18.2 |
| 9 | 5co | Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors | 3shz | 35.9 |
| 10 | 5bb | Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors | 4ia0 | 77 |
| 11 | 5fo | Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors | 3shy | 90.9 |
| 12 | wan | Crystal structure of the PDE5A catalytic domain in complex with a novel inhibitor | 3bjc | 110 |
| 13 | 5io | Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors | 4oew | 152 |
| 14 | ni5 | Crystal structure of PDE5A complexed with its inhibitor | 4g2y | 1000 |
| 15 | 5eo | Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors | 4oex | 1450 |
| 16 | 7ca | Crystal structure of PDE5A1 in complex with icarisid II | 2h44 | 1700 |