| Index | Ligand Name | Structure | PDB code | ligand desolvation |
| 1 | 4jz | Crystal structure of PYK2 complexed with PF-4618433 | 3fzt | 91.5 |
| 2 | b96 | Crystal Structure of PYK2 complexed with BIRB796 | 3fzs | 81.84 |
| 3 | p1e | Crystal structure of PYK2 in complex with Sulfoximine-substituted trifluoromethylpyrimidine analog | 3h3c | 80.43 |
| 4 | 3jz | Crystal structure of PYK2 complexed with PF-431396 | 3fzr | 73.72 |
| 5 | yam | Selectivity switch between FAK and Pyk2: Macrocyclization of FAK inhibitors improves Pyk2 potency | 5tob | 72.93 |
| 6 | 349 | Crystal structure of PYK2 complexed with PF-2318841 | 3et7 | 70.05 |