The Ligandable Human Proteome

Interleukin-1 receptor-associated kinase 4

Index	Ligand Name	Structure	PDB code	ligand desolvation
1	8cd	Crystal structure of IRAK4 in complex with compound 14	5uit	95.46
2	8cg	Crystal structure of IRAK4 in complex with compound 30	5uiu	93.91
3	8c1	Crystal structure of IRAK4 in complex with compound 12	5uis	92.57
4	6ye	Irak4-inhibitor co-structure	5kx8	91.9
5	xpy	Crystal structure of IRAK4 kinase domain with inhibitor	4y73	91.06
6	lrs	Structure of the IRAK4 kinase domain with compound 17	6o94	90.73
7	jx4	Crystal structure of human Interleukin-1 receptor associated Kinase 4 (IRAK 4, CID 100300) in complex with compound NCC00371481 (BSI 107591)	6mom	89.34
8	8by	Crystal structure of IRAK4 in complex with compound 11	5uir	89.11
9	4gd	Irak4-inhibitor co-structure	4yo6	88.93
10	kfd	IRAK4 bound to benzoxazole compound	6n8g	88.78
11	lty	Structure of the IRAK4 kinase domain with compound 5	6o9d	88.75
12	j8a	IRAK4 in complex with a type II inhibitor	6ega	87.75
13	lsv	Structure of the IRAK4 kinase domain with compound 41	6o95	87.15
14	9yy	CRYSTAL STRUCTURE OF IRAK-4 WITH A 4,6-DIAMINONICOTINAMIDE INHIBITOR (COMPOUND NUMBER 4)	5w84	86.88
15	4s1	Irak4-inhibitor co-structure	4ztl	86.81
16	ls7	Crystal structure of IRAK4 in complex with compound 23	6o8u	86.68
17	cjq	IRAK4 IN COMPLEX WITH inhibitor	6f3e	85.28
18	4s3	Irak4-inhibitor co-structure	4ztn	85.25
19	0li	IRAK4 in complex with Ponatinib	6eg9	85.02
20	42p	Irak4-inhibitor co-structure	4xs2	84.98
21	4gf	Irak4-inhibitor co-structure	4yp8	84.38
22	4s2	Irak4-inhibitor co-structure	4ztm	84.06
23	9ys	CRYSTAL STRUCTURE OF IRAK-4 WITH A 4,6-DIAMINONICOTINAMIDE INHIBITOR (COMPOUND NUMBER 9)	5w85	83.25
24	6qx	IRAK4 in complex with Compound 1	5k75	82.99
25	t20	Crystal Structure of IRAK-4	4rmz	82.52
26	76q	Irak4 kinase - compound 1 co-structure	5t1s	81.38
27	6qy	IRAK4 in complex with Compound 21	5k72	80.45
28	cjt	IRAK4 IN COMPLEX WITH inhibitor	6f3d	80.21
29	t12	Crystal structure of IRAK-4	2nru	80.05
30	k1h	IRAK4 IN COMPLEX WITH inhibitor	6rfi	77.97
31	6r1	IRAK4 in complex with Compound 28	5k76	77.24
32	cjn	IRAK4 IN COMPLEX WITH inhibitor	6f3g	77.19
33	6qz	IRAK4 in complex with AZ3864	5k7i	73.38
34	6r0	IRAK4 in complex with AZ3862	5k7g	72.1
35	ckn	IRAK4 IN COMPLEX WITH inhibitor	6f3i	71.61
36	k1e	IRAK4 IN COMPLEX WITH inhibitor	6rfj	70.42