The Ligandable Human Proteome

Tyrosine-protein kinase JAK1

Index	Ligand Name	Structure	PDB code	ligand desolvation
1	kes	Structure of the human JAK1 kinase domain with compound 20	6n79	97.26
2	kf4	Structure of the human JAK1 kinase domain with compound 54	6n7d	96.48
3	kep	Structure of the human JAK1 kinase domain with compound 21	6n78	94.73
4	key	Structure of the human JAK1 kinase domain with compound 38	6n7b	94.48
5	mi1	Crystal structures of JAK1 and JAK2 inhibitor complexes	3eyg	94.07
6	1q3	The Jak1 kinase domain in complex with compound 37	4k6z	93.66
7	9t6	Crystal structure of JAK1 in complex with peficitinib	6aah	93.66
8	d7d	Crystal Structure of JAK1 in complex with compound 25	6bbu	93.27
9	gyq	HUMAN JAK1 IN COMPLEX WITH LASW1393	6hzu	92.06
10	1j6	JAK1 kinase (JH1 domain) in complex with the inhibitor (TRANS-4-{2-[(1R)-1-HYDROXYETHYL]IMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDIN-1(6H)-YL}CYCLOHEXYL)ACETONITRILE	4ivc	91.12
11	0q2	JAK1 kinase (JH1 domain) in complex with compound 20	4ei4	90.61
12	1q4	JAK1 kinase (JH1 domain) in complex with compound 6	4k77	90.36
13	66p	Jak1 complex with 4-[(4-aminocyclohexyl)amino]-3-(1H-benzimidazol-2-yl)-1H-pyridin-2-one	5hx8	89.56
14	15t	JAK1 kinase (JH1 domain) in complex with compound 34	4ivd	88.65
15	g4j	Jak1 with compound 23	6dbn	87.81
16	kf1	Structure of the human JAK1 kinase domain with compound 56	6n7c	87.66
17	0nt	JAK1 kinase (JH1 domain) in complex with compound 26	4e5w	87.61
18	b7v	JAK1 complexed with compound 28	5wo4	86.87
19	kej	Structure of the human JAK1 kinase domain with compound 15	6n77	85.86
20	kev	Structure of the human JAK1 kinase domain with compound 39	6n7a	85.83
21	eyq	Human jak1 kinase domain in complex with inhibitor	6ggh	84.05
22	bfk	Human jak1 kinase domain in complex with compound 7	6elr	82.67
23	5jg	Human JAK1 kinase in complex with compound 30 at 2.30 Angstroms resolution	5e1e	82.12