The Ligandable Human Proteome

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Mast/stem cell growth factor receptor Kit

Protein kinase domain

IndexLigand NameStructurePDB codeligand desolvation
1jwyCrystal structure of KIT1 in complex with DP2976 via co-crystallization6mob95.84
2g4eStructure of c-Kit with allosteric inhibitor 3G86hh194.51
3stiSTRUCTURAL BASIS FOR THE AUTOINHIBITION AND STI-571 INHIBITION OF C-KIT TYROSINE KINASE1t4690.81
40liCrystal structure of KIT in complex with ponatinib4u0i88.5
5b49KIT kinase domain in complex with sunitinib3g0e85.76
6b49KIT kinase domain mutant D816H in complex with sunitinib3g0f81.97