The Ligandable Human Proteome

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Mitogen-activated protein kinase kinase kinase kinase 1

Protein kinase domain

IndexLigand NameStructurePDB codeligand desolvation
1b49Crystal structure of diphosphorylated HPK1 kinase domain in complex with sunitinib in the active state.6nfz75.6
2f97Crystal structure of HPK1 in complex an inhibitor G18586cqf72.39
3b49Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with sunitinib in the inactive state.6ng072.38