The Ligandable Human Proteome

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Tyrosine-protein kinase Mer

Protein kinase domain

IndexLigand NameStructurePDB codeligand desolvation
179yStructure-based optimization of 1H-imidazole-2-carboxamides as Axl kinase inhibitors utilizing a Mer mutant surrogate5tc085.38
224kCrystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC19174m3q81.08
37ysCrystal structure of the Mer kinase domain in complex with a macrocyclic inhibitor5u6c80.42
4mh7Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC18964mh778.62
57aeStructure-based optimization of 1H-imidazole-2-carboxamides as Axl kinase inhibitors utilizing a Mer mutant surrogate5td275.97
6olpCrystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor C523bpr73.1
7ckjCrystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC5693tcp72.33
8k0xCrystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC25415k0x70.45
94mhCrystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC18174mha67.45
106q1Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC24345k0k65.05