The Ligandable Human Proteome

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Proto-oncogene tyrosine-protein kinase receptor Ret

Protein kinase domain

IndexLigand NameStructurePDB codeligand desolvation
1dtqThe Discovery of 2-Substituted Phenol Quinazolines as Potent and Selective RET Kinase Inhibitors5amn90.19
2adnCrystal structure of RET tyrosine kinase domain bound to adenosine4ckj89.22
3adnCrystal Structure of oncogenic RET tyrosine kinase M918T bound to adenosine4cki85.54
4adnOncogenic point mutation of RET receptor tyrosine kinase6fek81.69
5zd6Crystal structure of phosphorylated RET tyrosine kinase domain complexed with the inhibitor ZD64742ivu76.72
6xinSTRUCTURE OF RET PROTEIN TYROSINE KINASE DOMAIN IN COMPLEX WITH NINTEDANIB6nec69.05