The Ligandable Human Proteome

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Receptor-interacting serine/threonine-protein kinase 2

Protein kinase domain

IndexLigand NameStructurePDB codeligand desolvation
1sr8RIP2 Kinase Catalytic Domain (1 - 310) complex with Biaryl Urea5ar797.53
2bw8Crystal structure of the kinase domain of human RIPK2 in complex with the activation loop targeting inhibitor CS-R356es097.34
39wsIdentification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases5w5j92.77
40liStructure of the kinase domain of human RIPK2 in complex with ponatinib4c8b86.32
5sb2RIP2 Kinase Catalytic Domain (1 - 310) complex with SB-2035805ar482.34
6iq7RIP2 Kinase Catalytic Domain (1 - 310) complex with Benzimidazole5ar576.73
79xaIdentification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases.5w5o72.3