Index | Ligand Name | Structure | PDB code | Compound Potency nM |
1 | 570 | THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND GI262570 AND CO-ACTIVATOR PEPTIDES. | 1fm9 | 1 |
2 | nsi | Crystal Structure of PPAR Gamma with N-sulfonyl-2-indole carboxamide ligands | 2hfp | 3 |
3 | unt | X-ray Crystal structure of the nuclear hormone receptor PPAR-gamma in a complex with a PPAR gamma/alpha dual agonist | 3ia6 | 3 |
4 | zaa | X-ray crystal structure of human ppar gamma with 2-(5-(3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzyl)-2-phenyl-2h-1,2,3-triazol-4-yl)acetic acid | 3bc5 | 5 |
5 | 7mv | Peroxisome proliferator-activated receptor gamma ligand binding domain in complex with a novel selectively PPAR gamma-modulating ligand VSP-51 | 5two | 8.06 |
6 | ro7 | Aleglitaar. a new. potent, and balanced dual ppara/g agonist for the treatment of type II diabetes | 3g9e | 19 |
7 | eha | Crystal structure of the ligand binding domain of human PPAR-gamma in complex with an agonist | 2f4b | 50 |
8 | drf | Ligand binding domain of the human peroxisome proliferator activated receptor gamma in complex with an agonist | 1nyx | 92 |
9 | 3ea | Crystal structure of the ligand binding domain of human PPAR-gamma im complex with an agonist | 2ath | 152 |
10 | l92 | X-ray Crystal structure of the nuclear hormone receptor PPAR-gamma in a complex with a PPAR gamma/alpha dual agonist | 2q8s | 185 |
11 | az2 | CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF HUMAN PPAR-GAMMA IN COMPLEX WITH THE AGONIST AZ 242 | 1i7i | 200 |
12 | c01 | Crystal Structure of Human PPAR-gamma Ligand Binding Domain Complexed with an Alpha-Aryloxyphenylacetic Acid Agonist | 1zeo | 210 |
13 | 208 | Structure-based Design of Indole Propionic Acids as Novel PPARag CO-Agonists | 2gtk | 251 |
14 | 3e7 | Crystal Structure of SR2067 bound to PPARgamma | 4r06 | 513 |
15 | drj | Crystal structure of the complex between PPARgamma and the agonist LT160 (ureidofibrate derivative) | 2i4j | 684.8 |
16 | ctm | Design and biological evaluation of novel, balanced dual PPARa/g agonists | 3fej | 740 |
17 | sfi | PPARgamma ligand binding domain in complex with sulindac sulfide | 4xuh | 1870 |
18 | drh | Crystal structure of the complex between PPARgamma and the partial agonist LT127 (ureidofibrate derivative). Structure obtained from crystals of the apo-form soaked for 30 days. | 2i4p | 1978 |
19 | drh | Crystal structure of the complex between PPARgamma and the partial agonist LT127 (ureidofibrate derivative). This structure has been obtained from crystals soaked for 6 hours. | 2i4z | 1978 |
20 | xcx | Crystal Structure of PPARgamma with an achiral ureidofibrate derivative (RT86) | 3r8i | 4500 |
21 | imn | Human PPARgamma ligand-binding domain in complex with indomethacin | 3ads | 9730 |
22 | 7va | X-ray Crystal Structure of the PPARgamma Ligand Binding Domain in Complex with Rivoglitazone | 5u5l | 1.4e+004 |
23 | imn | PPARgamma ligand binding domain in complex with indomethacin | 4xum | 2.13e+004 |