The Ligandable Human Proteome

Nuclear hormone receptor, ligand-binding domain

Index	Protein Name	Gene Name Primary	Gene Name Synonym	Uniprot ID	Most Potent Compound in PDB nM
1	Thyroid hormone receptor beta	THB	ERBA2 NR1A2 THR1	P10828	0.025
2	Progesterone receptor	PRGR	NR3C3	P06401	0.038
3	Estrogen receptor	ESR1	ESR NR3A1	P03372	0.05
4	Vitamin D3 receptor	VDR	NR1I1	P11473	0.065
5	Estrogen receptor beta	ESR2	ESTRB NR3A2	Q92731	0.19
6	Glucocorticoid receptor	GCR	GRL	P04150	0.268
7	Androgen receptor	ANDR	DHTR NR3C4	P10275	0.27
8	Mineralocorticoid receptor	MCR	MCR MLR	P08235	0.39
9	Nuclear receptor ROR-gamma	RORG	NR1F3 RORG RZRG	P51449	0.6
10	Retinoic acid receptor gamma	RARG	NR1B3	P13631	0.6
11	Peroxisome proliferator-activated receptor gamma	PPARG	NR1C3	P37231	1
12	Peroxisome proliferator-activated receptor delta	PPARD	NR1C2 PPARB	Q03181	1
13	Retinoic acid receptor beta	RARB	HAP NR1B2	P10826	2
14	Bile acid receptor	NR1H4	BAR FXR HRR1 RIP14	Q96RI1	4
15	Oxysterols receptor LXR-beta	NR1H2	LXRB NER UNR	P55055	7.94
16	Retinoic acid receptor RXR-alpha	RXRA	NR2B1	P19793	8
17	Nuclear receptor subfamily 1 group I member 2	NR1I2	PXR	O75469	10.8
18	Peroxisome proliferator-activated receptor alpha	PPARA	NR1C1 PPAR	Q07869	20
19	Oxysterols receptor LXR-alpha	NR1H3	LXRA	Q13133	27
20	Estrogen-related receptor gamma	ERR3	ERR3 ERRG2 KIAA0832 NR3B3	P62508	79
21	Steroid hormone receptor ERR1	ERR1	ERR1 ESRL1 NR3B1	P11474	190