Index | Ligand Name | Structure | PDB code | Compound Potency nM |
1 | 98n | Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds | 5ntw | 0.6 |
2 | 98e | Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds | 5ntp | 0.7 |
3 | 4y7 | Identification of a Novel Allosteric Binding Site for RORgt Inhibitors | 5c4u | 1.9 |
4 | 4q3 | RORgamma in complex with inverse agonist 4j. | 4zom | 3 |
5 | 4y5 | Identification of a Novel Allosteric Binding Site for RORgt Inhibitors | 5c4s | 3.8 |
6 | nbh | Crystal structure of the orphan nuclear receptor ROR(gamma)t ligand-binding domain in complex with small molecule ligand | 4nie | 20 |
7 | 4y6 | Identification of a Novel Allosteric Binding Site for RORgt Inhibitors | 5c4t | 21.8 |
8 | 76e | Ligand complex of RORg LBD | 5apj | 40 |
9 | vyi | Ligand complex of RORg LBD | 5aph | 60 |
10 | 3qq | Crystal structure of RORc in complex with a partial inverse agonist compound | 4wlb | 180 |
11 | 921 | X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with an agonist and SRC2 peptide | 5vb7 | 190 |
12 | 4p1 | RORgamma in complex with inverse agonist 16 | 4zjw | 220 |
13 | 92a | X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with an inverse agonist and SRC2 peptide | 5vb5 | 350 |
14 | 927 | X-ray co-structure of nuclear receptor ROR-gammat Ligand Binding Domain with an inverse agonist and SRC2 peptide | 5vb6 | 430 |
15 | zbd | X-ray co-structure of nuclear receptor ROR-GAMMAT + SRC2 peptide with a benzothiadiazole dioxide inverse agonist | 4ymq | 1600 |