The Ligandable Human Proteome

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Thyroid hormone receptor beta

Nuclear hormone receptor, ligand-binding domain

IndexLigand NameStructurePDB codeCompound Potency nM
1oefHuman Thyroid hormone receptor beta ligand binding domain in complex with KB1310842j4a0.025
2pfaCRYSTAL STRUCTURE OF HUMAN TR BETA LIGAND-BINDING DOMAIN COMPLEXED WITH A POTENT SUBTYPE-SELECTIVE THYROMIMETIC1n460.03
34hyTR Receptor Mutations Conferring Hormone Resistance and Reduced Corepressor Release Exhibit Decreased Stability in the Nterminal LBD1nq00.048
4t3Thyroxine-Thyroid Hormone Receptor Interactions1xzx0.06
5t3Crystal Structure of T3-Bound Thyroid Hormone Receptor3gws0.081
6b72Structure of TR-beta bound to selective thyromimetic GC-13imy0.2
7g24Crystal Structure of Human Thyroid Hormone Receptor beta LBD in complex with specific agonist GC-241q4x0.33
8442Crystal structure of the thyroid hormone receptor beta ligand binding domain in complex with a beta selective compound1r6g0.62
94hyCrystal Structure of TR-beta bound to the selective thyromimetic TRIAC3jzc2.94
10ih5Thyroid receptor beta1 in complex with a beta-selective ligand1nax370