| Index | Ligand Name | Structure | PDB code | ligand desolvation |
| 1 | 0ny | Crystal structure of human PDE1B bound to inhibitor 19A (7,8-dimethoxy-N-[(2S)-1-(3-methyl-1H-pyrazol-5-yl)propan-2-yl]quinazolin-4-amine) | 4npw | 90.63 |
| 2 | 0ny | PDE1b complexed with compound 3S | 5w6e | 90.26 |
| 3 | 0nk | Crystal structure of human PDE1B bound to inhibitor 7A (6,7,8-trimethoxy-N-(pentan-3-yl)quinazolin-4-amine) | 4npv | 83.47 |
| 4 | 8hm | Crystal structure of human PDE1B catalytic domain in complex with inhibitor 16j (6-(4-Methoxybenzyl)-9-((tetrahydro-2H-pyran-4-yl)methyl)-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one) | 5uoy | 82.89 |
| 5 | 8hp | Crystal structure of human PDE1B catalytic domain in complex with inhibitor 3 (6-(4-chlorobenzyl)-8,9,10,11-tetrahydrobenzo[4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one) | 5up0 | 80.09 |
| 6 | 4qj | Crystal structure of human PDE1B with inhibitor 3 | 5b25 | 79.33 |