The Ligandable Human Proteome

cGMP-specific 3',5'-cyclic phosphodiesterase

3'5'-cyclic nucleotide phosphodiesterase, catalytic domain

Index	Ligand Name	Structure	PDB code	ligand desolvation
1	7ca	Crystal structure of PDE5A1 in complex with icarisid II	2h44	98.11
2	9m0	Crystal structure of PDE5 in complex with inhibitor LW1634	5zz2	88.42
3	cia	Crystal structure of Human Phosphodiesterase 5 complexed with tadalafil(Cialis)	1udu	88.28
4	ibm	Crystal structure of PDE5A1-IBMX	1rkp	87.16
5	via	Crystal structure of PDE5 in complex with sildenafil	2h42	86.91
6	24e	Crystal structure of PDE5 in complex with inhibitor 5R	4md6	86.33
7	vdn	Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil	3b2r	82.34
8	via	Crystal structure of Human Phosphodiesterase 5 complexed with Sildenafil(Viagra)	1udt	80.38
9	5bo	Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors	3sie	77.36
10	wan	Crystal structure of the PDE5A catalytic domain in complex with a novel inhibitor	3bjc	76.78
11	vdn	Crystal structure of Human Phosphodiesterase 5 complexed with Vardenafil(Levitra)	1uho	75.34
12	5io	Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors	4oew	75.14
13	5ba	Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors	4i9z	74.49
14	5fo	Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors	3shy	72.12
15	9t9	Crystal structure of PDE5 in complex with inhibitor LW1805	6acb	71.57
16	ni0	Crystal structure of PDE5A in complex with its inhibitor	4g2w	71.47
17	5bb	Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors	4ia0	70.85
18	ni5	Crystal structure of PDE5A complexed with its inhibitor	4g2y	70.06
19	5eo	Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors	4oex	69.65
20	5co	Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors	3shz	67.22