The Ligandable Human Proteome


Nuclear hormone receptor, ligand-binding domain

IndexProtein NameGene Name PrimaryGene Name SynonymUniprot IDHighest desolvation of bound compounds in the PDB
1Androgen receptor ANDRDHTR NR3C4P10275100
2Thyroid hormone receptor beta THBERBA2 NR1A2 THR1P10828100
3Retinoic acid receptor gamma RARGNR1B3P13631100
4Estrogen receptor ESR1ESR NR3A1P03372100
5Estrogen receptor beta ESR2ESTRB NR3A2Q92731100
6Progesterone receptor PRGRNR3C3P06401100
7Mineralocorticoid receptor MCRMCR MLRP08235100
8Glucocorticoid receptor GCRGRLP0415099.92
9Bile acid receptor NR1H4BAR FXR HRR1 RIP14Q96RI199.88
10Nuclear receptor ROR-gamma RORGNR1F3 RORG RZRGP5144999.87
11Retinoic acid receptor RXR-alpha RXRANR2B1P1979399.78
12Oxysterols receptor LXR-beta NR1H2LXRB NER UNRP5505599.76
13Vitamin D3 receptor VDRNR1I1P1147399.74
14Peroxisome proliferator-activated receptor gamma PPARGNR1C3P3723199.71
15Retinoic acid receptor alpha RARANR1B1P1027699.68
16Retinoic acid receptor beta RARBHAP NR1B2P1082699.6
17Estrogen-related receptor gamma ERR3ERR3 ERRG2 KIAA0832 NR3B3P6250899.34
18Peroxisome proliferator-activated receptor delta PPARDNR1C2 PPARBQ0318198.69
19Retinoic acid receptor RXR-beta RXRBNR2B2P2870298.65
20Nuclear receptor subfamily 1 group I member 2 NR1I2PXRO7546998.64
21Oxysterols receptor LXR-alpha NR1H3LXRAQ1313398.2
22Peroxisome proliferator-activated receptor alpha PPARANR1C1 PPARQ0786998.17
23Nuclear receptor subfamily 5 group A member 2 NR5A2B1F CPF FTFO0048297.77
24Nuclear receptor ROR-alpha RORANR1F1 RZRAP3539896.92
25Steroid hormone receptor ERR1 ERR1ERR1 ESRL1 NR3B1P1147495.43